Testing Cluster-level Random Effect in Joint Models of Clinical Trial Data
نویسندگان
چکیده
........................................................................................................................................... 2 Co-Authorship ................................................................................................................................. 4 Acknowledgements .......................................................................................................................... 5 Statement of Originality ................................................................................................................... 6 List of Figures .................................................................................................................................. 9 List of Tables ................................................................................................................................. 10 Chapter 1 Literature Review and Introduction .............................................................................. 11 1.1 Cluster effect in multicenter clinical trials ........................................................................... 11 1.1.1 Consequences of Cluster Effects ................................................................................... 11 1.1.2 Correcting For Cluster Effect in Practice ...................................................................... 12 1.1.3 Asymptotic Approach of Detecting Cluster-level Random Effect ................................ 14 1.2 Bootstrap .............................................................................................................................. 16 1.2.
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تاریخ انتشار 2014